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USMLE Step 2 CK Buzzwords Buzzwords that should ring a bell in USMLE Step 2 CK exam.


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Old 06-02-2011
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RBC Schistocytes and Helmet cells

Schistocytes (AKA helmet cells) are buzzwords for the following conditions:
  1. DIC
  2. HUS (hemolytic uremic syndrome)
  3. TTP (thrombotic thrombocytopenic purpura)
  4. Mechanical /prosthetic valves
  5. Calcified Aortic valves
If somebody knows more, then add it.

Thanks!
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Old 06-02-2011
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Schistocytes
Schistocytes are red cell fragments which are formed when fibrin strands come in contact with circulating red cells. The strands cut a small piece from the original cell. Several descriptive names have been used for schistocytes, depending on the resulting shape of the fragment. These include pre-keratocyte, also described as a blister cell, and keratocyte, also described as a helmet cell or horn cell. Regardless of the terminology, these cells are part of the more inclusive group designated as schistocytes and should be reported as such.

Schistocytes can be seen in disseminated intravascular coagulation (DIC), micropathic hemolytic anemia, glomerulonephritis, and hemolytic anemia resulting from mechanical trauma to the red blood cells (such as severe burns
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Old 06-03-2011
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Quote:
Originally Posted by miss patho View Post
Schistocytes
Schistocytes are red cell fragments which are formed when fibrin strands come in contact with circulating red cells. The strands cut a small piece from the original cell. Several descriptive names have been used for schistocytes, depending on the resulting shape of the fragment. These include pre-keratocyte, also described as a blister cell, and keratocyte, also described as a helmet cell or horn cell. Regardless of the terminology, these cells are part of the more inclusive group designated as schistocytes and should be reported as such.

Schistocytes can be seen in disseminated intravascular coagulation (DIC), micropathic hemolytic anemia, glomerulonephritis, and hemolytic anemia resulting from mechanical trauma to the red blood cells (such as severe burns
Yes. Thanks Miss patho.

They are red blood cell fragments, also known as "bite cell". Basically in all conditions where red cell membrane damage encountered during passage through vessels.
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Old 06-03-2011
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@ 1TA2B:

well bite cells are seen in G6PD deficiency alone...and they are so called because the spleen tries to remove the heinz body from RBCs ...but in doin so spleen also remove a part of the RBC's membrane...and hence make it look like the bite cell
and the other name of Schistocytes is helmet cells ....

kindly correct me if i am wrong

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shistocytes or helmet cells also present in micronangiopathic hemolytic anemia ...
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Old 06-04-2011
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Default hey

hey
i m nogt sure but it also seen in malignant hypertension..........
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Old 06-03-2014
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Quote:
Originally Posted by mle guy View Post
Schistocytes (AKA helmet cells) are buzzwords for the following conditions:
  1. DIC
  2. HUS (hemolytic uremic syndrome)
  3. TTP (thrombotic thrombocytopenic purpura)
  4. Mechanical /prosthetic valves
  5. Calcified Aortic valves
If somebody knows more, then add it.

Thanks!

DIC
HUS (hemolytic uremic syndrome)
TTP (thrombotic thrombocytopenic purpura)
SEPSIS! I wanted to add sepsis!



How do mechanical values and calcified aortic valvues cause schistocyte?
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Old 06-27-2014
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Warning! difference between schystocyte, helmet cell and bite cell

according to my knowledge:
- schystocyte and helmet cells: hemolytic anemia, valvulopathies etc;
- bite cell--> ONLY in G6Pdef!

please dont mix up!!!!
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