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USMLE Step 2 CK Classic Clues Classic clues seen in clinical case scenarios in USMLE Step 2 CK questions.


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  #1  
Old 02-15-2010
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Blood Leg swelling + Dyspnea + Abortions

Whenever you see a female patient with any of the following clinical features then you have to suspect Antiphospholipid syndrome and it's always asked about in CK exam.
The features are:
  • DVT (leg swelling)
  • Pulmonary embolism (dyspnea, chest pain, cyanosis, sudden death, ...etc)
  • H/O repeated abortions
  • Increased PTT
  • Thrombocytopenia
  • Livedo reticularis
Of course there are several other manifestations of APS but these are the main ones that are commonly mentioned.
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  #2  
Old 08-11-2011
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Correct Answer

Quote:
Originally Posted by lee-usmle View Post
Whenever you see a female patient with any of the following clinical features then you have to suspect Antiphospholipid syndrome and it's always asked about in CK exam.
The features are:
  • DVT (leg swelling)
  • Pulmonary embolism (dyspnea, chest pain, cyanosis, sudden death, ...etc)
  • H/O repeated abortions
  • Increased PTT
  • Thrombocytopenia
  • Livedo reticularis
Of course there are several other manifestations of APS but these are the main ones that are commonly mentioned.
Here I want to add one more thing,whenever PTT is raised that usually lead to bleeding disorders but its a paradox here a thromboembolic disease with a raised PTT.The reason is we use phospholipid Abs in the lab while measuring PTT.
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  #3  
Old 07-09-2016
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thanks........
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  #4  
Old 08-06-2016
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Useful info
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Hematology-, Immunology-, Internal-Medicine-, ObGyn-

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