Platypnea and Orthodeoxia - USMLE Forums
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USMLE Step 2 CK Classic Clues Classic clues seen in clinical case scenarios in USMLE Step 2 CK questions.

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Old 07-02-2010
pampiniform's Avatar
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Lungs Platypnea and Orthodeoxia

If the boards give you a question describing a patient with decrease saturation (orthodeoxia) and dyspnea (playpnea) while in the upright position and he also have liver disease then this is certainly HepatoPulmonary syndrome.

They have platypnea and orthodeoxia because there's increased pulmonary vasodilation (for unknown reason) which results in ventilation perfusion mismatch (shunt) because more blood is going than there's alveoli to exchange oxygen with. This shunt increases in the upright position.
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Old 07-26-2010
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I agree hello

thanks for your good post
at least in resources i've read ,there isn't any mention to orthodeoxia except hepatopulmonary disorder.
i want to say that even without mention to hepatic disease in exam question
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Gastroenterology-, Internal-Medicine-, Pulmonology-

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