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Old 06-16-2011
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Liver Hepatitis serology!

Hepatitis serology test shows below!
HepBsAg positive
anti-HepBsAb negative
anti-HepBcAb positive


What does the patient most likely have?
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Old 06-16-2011
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This patient just had a hep B and is making the first antibodies anti-HepBcAb however he still is hepBsAg positive so he most likely will have chronic hepatitis..Please correct me if i m wrong
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Old 06-16-2011
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Quote:
Originally Posted by 1TA2B View Post
Hepatitis serology test shows below!
HepBsAg positive
anti-HepBsAb negative
anti-HepBcAb positive


What does the patient most likely have?
acute or chronic hepatitis
if
anti-HepBcAb positive and HepBsAg negative
window period
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Old 06-17-2011
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If the anti-Hbc is IgM, then this is definately an acute hepatitis.
If the anti-Hbc is IgG, then this is chronic hepatitis.
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Old 06-17-2011
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It s not window period because during window infection the only positive is HBcAb IgM. If he is HBsAg positive and HbcAb IgM positive and HbsAb IgG negative then it's an acute infection..Kaplan Notes Step 1 Microbiology..
1TA2B please give us the answers
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Old 06-17-2011
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Yes indeed acute hepatitis B!

I feel that anti-hepB C Ab should be specified in the question! M for acute and G for chronic as per fellow add1.

See the explanation! (usmle consult)

The pattern for acute infection with hepatitis B is as follows: HepBsAg positive, anti-HepBsAb negative, anti-HepBcAb positive (in particular the IgM).

Chronic infection with hepatitis B pattern is as follows: HepBsAg positive, anti-HepBsAb negative, and anti-HBcAb positive (in particular the IgG).
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