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Old 07-15-2011
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Question A 54 year old man

A 54 year old man presents to your office complaining of headache and blurred vision for the past several months. He also says that his family comments that his face looks different, his nose being bigger than it used to be. In addition, he says hi shoes feel tighter. On physical he has a coarse facial features with a prominent mandible and widely spaced incisors. MRI of the brain reveals a mass in the pituitary. This patient may be at increased risk of developping which of the following?

A. Colon cancer
B. Pancreatic adenocarcinoma
C. Hepatocellular carcinoma
D. Lung cancer
E. Malignant brain tumor
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  #2  
Old 07-15-2011
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I am not sure, but I choose A. Colon cancer. Other cancers have some specific risk factors and I do not recall that any of those is Acromegaly.
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Old 07-15-2011
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Acromegaly may leads to colon polyp....so mind just hitting on > A. Colon cancer
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Old 07-16-2011
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A) colon cancer
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Old 07-16-2011
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a) colon cancer
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Old 07-16-2011
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colon cancer

complication of acromegaly are
  • Arthritis
  • Cardiovascular disease
  • Carpal tunnel syndrome
  • Colonic polyps
  • Glucose intolerance or diabetes
  • High blood pressure
  • Hypopituitarism
  • Sleep apnea
  • Spinal cord compression
  • Uterine fibroids
  • Vision abnormalities

from pub med
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Old 07-17-2011
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waiting for answer !
__________________
I'm Predictable In The Unpredictable Future !
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Old 07-17-2011
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The correct answer is A. Colon cancer This patien has acromegaly, a condition caused by excessive levels of GH, most commonly due to a pituitary adenoma. Blurred vision is due to compression of the optic chiasm by the pituitary mass, and patients may also exhibit frontal bossing, mandibular groeth, coarsened facial features, and increased foot and hand size due to bony overgrowth ans soft tissue swelling. Patients with acromegaly may be at increase risk for developping colonic polyps and colonic malignancy. They are also at risk of developping coronary artery disease, cardimyopathy, hypertension, DM, and sleep apnea
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Endocrinology-, Internal-Medicine-, Step-2-Questions

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