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  #1  
Old 07-17-2011
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Thyroid Risk Factor for this thyroid cancer!

A 60 year old man presents to your office with dysphagia, facial flushing, and diarrhea. Physical reveals a goiter and mild cervical lymphadenopathy. based on thyroid function test results, he is referred to a surgeon for total thyroidectomy, which reveals medullary carcinoma. He is currently being treated with thyroid hormone suppression therapy. Which of the following is the most significant risk factor for this form of thyroid cancer?

A. Alcohol
B. Smoking
C. Iodine exposure
D. Radiation of the neck for enlarged tonsils as a child
E. Genetic risk factor
F. Viral infection
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  #2  
Old 07-17-2011
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I think it's E. Genetic risk factor (component of MEN2 syndrome/germline RET mutation)
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Old 07-17-2011
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the answer is genetic

It is reasonable to test all patients with MTC for RET mutations, as genetic counseling and testing of family members can be offered to those individuals who test positive for mutations.
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Old 07-17-2011
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E.Genetic........
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Old 07-18-2011
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E genetic it is
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Old 07-18-2011
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Im thinking MEN syndrome so Genetic risk factor is the greatest

Alcohol and smokingi havent heard of it causing any thyroid cancer

Iodine is needed by the thyroid so why would it cause caner? (unless its the radioactive kind)

Radiation itself usually cause fibrosis as for long term cancer risk well to be honest i think it can be anything but i think its more likely follicular or papillary.

Viral hmm i seem tho think it has a relation but i cant remember any

can some one chime in on that? name a viral cause of thyroid cancer?
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Old 07-18-2011
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The correct answer is E. Medullary carcinoma accounts for about 5% of all thyroid cancers and is familial in up to 25% of cases.
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Old 07-18-2011
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E. Genetic risk factor
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Old 07-18-2011
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E. Genetic risk factor
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Endocrinology-, Oncology-, Preventive-Medicine-, Step-2-Questions

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