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  #1  
Old 08-09-2011
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Drug Malaria Meds Question

A 15 year old African American with a history of seizure travels to panama and upon his return presents to the doctor with muscle pain, fever, malaise. His blood smear shows shistocytes, Heinz bodies, dysmorphic RBC with parasite, Platelets 90,000, WBC 16000 etc...what is the appropriate treatment for this individual?
A) chloroquine
B) atovoqone & proguanil
C) mefloquine
D) Dapsone
E) DOxycycline..
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Old 08-09-2011
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Patient with seizures aquires malaria so A, C, E Should not be given since it may decrease seizure threshold...

D. dapsone should be cautiously used in g6pd deficiency and as well used in combination ...so better to avoid drug having contraindications...
so my answer is B. atovoqone & proguanil.......
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Old 08-09-2011
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hard q
shistocyte with thrombocytopenia and neuro symptoms lead us to ttp
bite cell with henz bodied lead us to g6pd
so malaria infection cause heamolytic anemia
so the answer to rx the cause

B...atovoqone & proguanil
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  #4  
Old 08-09-2011
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B...atovoqone & proguanil
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Old 08-09-2011
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Sorry to disappoint you all but you guys are all wrong lol...wow one question that has the guru's stumped...
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Old 08-09-2011
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i'l go with D
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Old 08-09-2011
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B...atovoqone & proguanil
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Old 08-09-2011
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Still nope....really lol
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Old 08-09-2011
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i'd go with a) Chloroquine.
Panama is sensitive to this drug in contrast with south east asia and africa, so it's still A isn't it?
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Old 08-09-2011
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Quote:
Originally Posted by cool_atomic View Post
i'd go with a) Chloroquine.
Panama is sensitive to this drug in contrast with south east asia and africa, so it's still A isn't it?
lmaoooo..No and Panama is one of the countries in central america that you cant use chloroquine...its specifically stated in MTB2
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Old 08-09-2011
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doxycycline.........
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Old 08-10-2011
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Quote:
Originally Posted by Kais_MD View Post
lmaoooo..No and Panama is one of the countries in central america that you cant use chloroquine...its specifically stated in MTB2
and what does "lmaoooo" mean?
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Old 08-10-2011
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yeah, and i forgot.... i remembered the whole central america thing as chloroquine.....it's mentioned "except panama" and mefloquine can be used there: source kaplan IM: Chapter 1: travel medicine. but now i am confused b/w mefloquine and doxy!!!
Can we have the explanation now?
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Old 08-10-2011
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Even doxycycline cannot be used since it is used for prophylaxis only that too in combination only and cannot be used for initial treatment even though organism is sensitive.........
so we are left with mefloquine??
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Old 08-10-2011
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Quote:
Originally Posted by Kais_MD View Post
A 15 year old African American with a history of seizure travels to panama and upon his return presents to the doctor with muscle pain, fever, malaise. His blood smear shows shistocytes, Heinz bodies, dysmorphic RBC with parasite, Platelets 90,000, WBC 16000 etc...what is the appropriate treatment for this individual?
A) chloroquine
B) atovoqone & proguanil
C) mefloquine
D) Dapsone
E) DOxycycline..
ok here it goes..>Chloroquine cant be used because its one of the areas in central america where chloroquine isnt sensitive.....Atovoquone and proguanil is used in pregnancy...mefloquine cant be used because he has a seizure d/o......Dapsone cant be used because he has g6pd....that leaves DOxy which is acceptable for malaria next in line after mefloquine if there are contraindications to other drugs ....MTB 2
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Old 08-10-2011
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Too many parameters to be considered. Miss patho's thought process seems right to me. I will also go for B. I know u said tht was wrong!!!

But no other ideas...
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Old 08-10-2011
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Quote:
Originally Posted by podebrad View Post
Too many parameters to be considered. Miss patho's thought process seems right to me. I will also go for B. I know u said tht was wrong!!!

But no other ideas...
i know..but believe it or not ..WOrld has some questions that have more parameters..I just hope its not the case in step 2....although an easy question but it just seems annoying because its very easy to miss....
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