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Old 09-22-2011
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Default AIDS patient with pulmonary & CNS infection

An AIDS patient presented with cough, fever, chills, chest pain, fatigability, and some weight loss. No improvement with penicillin. He developed severe headache & Rt sided weakness. CT scan demonstrated several metastatic brain abscesses. Biopsy of one of these lesions demonstrates beaded, branching, filamentous gram-positive bacteria that are weakly acid fast. Which of the following is the most likely causative organism?
1. Burkholderia .
2. Aspergillus
3. D. Francisella
4. Nocardia
5. Actinomyces
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Old 09-22-2011
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it's Nocardia....
gram positive rod which is weakly acid fast and is Aerobic...
causes disease in immunocompromised eg in HIV, transplant, pt on chemo, lymphoma etc
treatment of choice trimethoprim/sulfamethozole


actinomyces is also gram positive rod which is acid fast but anaerobic
and it causes disease in healthy person..
treatment penicillin G
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Old 09-22-2011
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4. Nocardia.
Busterbee already gave a good explanation.
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