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Old 09-23-2011
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Default mortality benefits in CHF/STEMI

ACEI, ARB, spirolactone, b-blockers have mortality benefits in CHF whereas digoxin and loop diuretics reduce symptoms and hospitalisation.
aspirin, b-blocker, ACEI have mortality benefits in STEMI
what about thaizide diuretics?
It is given that thiazide too decreases CVS mortality and morbidity equal to ACEI/dihydropyridine CCB in uworld.

what do u think guys about thiazide ? Iv diuretic is given intially for symptomatic relief in heart failure.
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Old 09-24-2011
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The following lower mortality in STEMI:
  • Aspirin.
  • Beta Blockers.
  • TPA.
  • Angioplasty.
  • Clopidogrel (DONOT Use Ticlopidine associated with TTP & neutropenia)
  • Statin if LDL is high.
  • ACE if EF is low.
Among all the therapies, the most significant mortality benefits have come form the use of Aspirin because it decreases the incidence of Acute MI. So all patients of ischemic heart disease are put on aspirin (if contraindicated Clopidogrel).


The following lower mortality in systolic dysfunction-dilated cardiomyopathy:
  • Beta blocker.
  • ACE & ARBs
  • Implantable defibrillator with dilated ischemic cardiomyopathy .
  • Spironolactone.
Diuretics do not lower mortality.
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Old 09-24-2011
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Quote:
Originally Posted by iron View Post
ACEI, ARB, spirolactone, b-blockers have mortality benefits in CHF whereas digoxin and loop diuretics reduce symptoms and hospitalisation.
aspirin, b-blocker, ACEI have mortality benefits in STEMI
what about thaizide diuretics?
It is given that thiazide too decreases CVS mortality and morbidity equal to ACEI/dihydropyridine CCB in uworld.

what do u think guys about thiazide ? Iv diuretic is given intially for symptomatic relief in heart failure.
IV diuretics are given for initial treatment of CHF but NOT thiazides!!! You give IV loop diuretics. No mortality benefit.
As for the rest, ag2011n has explained already.
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Old 09-24-2011
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Quote:
Originally Posted by dr_mhm View Post
IV diuretics are given for initial treatment of CHF but NOT thiazides!!! You give IV loop diuretics. No mortality benefit.
As for the rest, ag2011n has explained already.
I noticed that while reading one of the questions of uworld .
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