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Old 11-02-2011
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Smile PTH and Mg

I'm watching videos from kaplan for step 2 and the guy says that Mg is important for the interaction of PTH in the osteoclasts receptors.
From what I learned from step 1 is that osteoclasts don't have receptors for PTH, is by M-CSF and RANK-L produced by the osteoclasts that PTH controls indirectly osteoclasts.
Can someone explains me where Mg plays a role here.
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Old 11-02-2011
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Ma can cause:
1) impaired synthesis of D3
2) cellular resistance to PTH
3) very low Mg can cause a defect in PTH secretions
Sorry i dont know at the receptor level
i think it is just sufficient to know that low Mg cause low PTH , low Ca and high Phosphate, and dietary deficient is usuallu in a setting of alcoholism. I hope it helps you
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The above post was thanked by:
dr.digant (11-04-2011)


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