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Old 03-09-2010
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Drug AntiTB drug cause sideroblastic anemia

What antitubercular drugs causes sideroblastic anemia ?
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Old 03-09-2010
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I think it's INH.
Do you know of any other drugs ?
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Old 03-09-2010
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A pt with prussian blue stain positive . drug options are ..
1. streptomycin
2. pyrazinamade
3. ethumbutol
4. kanamycin
5. rifampin
6. cycloserine

Which 2 drugs causes above positive blood findings and why ?
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Old 03-09-2010
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Quote:
Originally Posted by FSUSTC View Post
A pt with prussian blue stain positive . drug options are ..
1. streptomycin
2. pyrazinamade
3. ethumbutol
4. kanamycin
5. rifampin
6. cycloserine

Which 2 drugs causes above positive blood findings and why ?
Prussian Blue stain of what? I assume you mean the bone marrow. Of the list you mentioned only cycloserine causes sideroblastic rings in the bone marrow. I don't think there are two drugs in the list.
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Old 03-09-2010
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Sorry i really made the ques very short ....its prussian blue stain of RBC in bone marrow .... yes beside INH & cycloserine there is another one ........
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Old 03-09-2010
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Quote:
Originally Posted by FSUSTC View Post
Sorry i really made the ques very short ....its prussian blue stain of RBC in bone marrow .... yes beside INH & cycloserine there is another one ........
Is it ethambutol
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Old 03-09-2010
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Anti TB drug that cause sideroblastic anemia ... INH , cycloserine , pyrazinamide ..... as these 3 drugs has anti Vit B6 properties ...
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Old 03-09-2010
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Thank you for the great info
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Hematology-, Internal-Medicine-, Pharmacology-

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