Gastroschisis; Silo formation and third spacing! - USMLE Forums
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Old 12-10-2011
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GIT Gastroschisis; Silo formation and third spacing!

Hi all:
On MTBCK p.410 concerning gastroschsis, can someone please explain what does that mean: " silo formation" and " overly agressive surgical reintroduction of the bowel will lead to third spacing and bowel infarction (what does this third spacing mean?)"

Thank you!
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Old 12-10-2011
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I don't have the actual source you are referring to.

"Silo" just means anything for storing a bulk of material. In this case, it covers the bowel and then gradual daily reduction follows.

"Third space" is an interesting concept. The way I like to think of it is that if you imagine ECF as divided into vascular space, interstitial space and "third space". Normally ECF stays in the first two spaces. Pathological collection in the third space (which normally don't have a significant amount of fluid) is known as "third spacing" and can deplete fluid in the other normal spaces potentially leading to hypovolaemic shock.

Examples of "third spacing" can be excessive collection of fluid in peritoneal cavity, pleural space, burn sites (which then evaporates). This may be due to a number of pathologies from bowel perforation, pancreatitis, pleural effusion, peritonitis etc.
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chienpolska (12-10-2011), donofitaly (12-12-2011), gofish6060 (06-06-2015)
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Old 11-13-2014
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Great answer,!
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