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Old 01-10-2012
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Question Serum calcium & pancreatitis

Although hyperparathyroidism is one of the causes of acute pancreatitis, serum calcium below 2mmol/l is one of the positive findings. Any clarification?

And why is chronic pancreatitis associated with elevated serum calcium levels?
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Old 01-10-2012
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“Studies of pathophysiology of acute pancreatitis indicate that the crucial early events occur within the acinar cells. Initiating events that result in abnormal sustained increase of acinar cytosolic calcium may precipitate pancreatitis. Initiating factors, such as ethanol abuse, hyperlipidemia and ductal hypertension may induce pancreatitis through the common mechanism of raising acinar calcium concentrations.”
Clinical pathology of pancreatic disorders-John Alfred Lott

The exact mechanism of how alcohol, hyperlipidemia and pancreatic duct obstruction causes elevated calcium levels are particular for each one and further described in the text. You can go to Google Books and you will have plenty of books describing these pathophysiologies, i’d write it for you but its too long :s
Good luck!
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drzamzam (01-10-2012), mayursn39 (01-10-2012)
Old 01-11-2012
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The reason for your first query is that in acute pancreatitis there is fat necrosis so the calcium is used up in fat saponification.

I can't think of something about your second query.
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Old 01-11-2012
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hyperCA+2 will cause spasm of sphincter of Oddi -----> pancreatitis
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