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Old 02-19-2012
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Question Steroids and increased BUN/creatine ratio

Hi all:

For patients administering steroids, why there is increased BUN/creatine ratio? Is this due to the catabolic effects of steroid on the muscles?

Thank you!!
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Old 12-27-2012
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YES.

I read it somewhere before, and can't remember the source.
dt break down of Amino Acids
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Old 12-27-2012
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Quote:
Originally Posted by chienpolska View Post
Hi all:

For patients administering steroids, why there is increased BUN/creatine ratio? Is this due to the catabolic effects of steroid on the muscles?

Thank you!!
This is first time listening about the damaging effects of steroids on the kidney, but if this occurs may be your explanation is correct.
Waiting to know the definitive answer
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Old 12-27-2012
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Quote:
Originally Posted by heartbeat View Post
This is first time listening about the damaging effects of steroids on the kidney, but if this occurs may be your explanation is correct.
Waiting to know the definitive answer
I think it has to do with its inhitory effect on Prostaglandins in afferent arteriole,causing reduced GFR & Renal plasma flow
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