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Old 03-22-2012
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Question Depression + hypersomnia; best initial therapy

A 29-year-old man complains of a complete lack of energy or motivation to accomplish his daily required tasks over the last month. He has been sleeping 12 to 14 hours a day in the last month but normally sleeps 6 to 7 hours a day. When he awakes, he feels unrefreshed and strongly desires a nap several times a day. Consequently, he has lost interest in his hobbies, such as playing soccer. He feels extremely guilty about his current life situation and is especially concerned about his lack of energy and desire to constantly sleep. Over the last month, he has unintentionally lost 2 kg (4 lb 6 oz). He specifically denies suicide ideation. His previous medical history is unremarkable, and he does not take any regular medications. He does not drink or use tobacco. Physical examination is within normal limits, and laboratory evaluation reveals fasting euglycemia and a normal thyroid-stimulating hormone (TSH) level. What is the most appropriate initial pharmacotherapy?

A. Amitriptyline
B. Bupropion
C. Doxepin
D. Mirtazapine
E. Trazodone
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Old 03-23-2012
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Answer is B , because a, c, d, e all causes sedation, so bupropion is least sedation as compare to others
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Old 03-23-2012
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Default Hypersomnia with depression

Hi
I chose a Bupropion hydrochloride
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