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Old 04-23-2012
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Lungs Asthma versus COPD Longterm Management

please help, i am so confused with this:

how does acute exacerbation and long term management in Asthma and COPD differ? .... i confuse them all the time...

anyone please help.. thank you
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Old 04-24-2012
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One way to remember the difference is that in COPD steroids does not help much while they are the mainstay of treatment in Asthma.
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Old 04-24-2012
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COPD (Acute Exacerbation):

1. Anticholinergic drugs like Ipratropium provides short-acting rapid relief of COPD symptoms.
2. β2 agonists like Salbutamol and terbutaline are widely used short acting β2 agonists and provide rapid relief of COPD symptoms.

COPD (Long Term Management):

1. Long acting β2 agonists (LABAs) such as salmeterol and formoterol are used as maintenance therapy.
2. Corticosteroids are used to treat and prevent acute exacerbations of COPD but are much less useful since inflammation/edema/smooth muscle hypertrophy of airways is not the primary pathology in COPD.
3. Supplemental oxygen is given to people with COPD who have low oxygen levels in the body and is the only t/t which lowers mortality

Asthma (Acute Exacerbation):
1. Short acting beta2-adrenoceptor agonists (SABA), such as salbutamol (albuterol USAN) are the first line treatment for asthma symptoms.
2. Glucocorticoids (short course systemic if inhaled not effective) but takes time for the effect.


Asthma (Long Term Management):
1. Long acting beta-adrenoceptor agonists (LABA) have at least a 12-hour effect (especially useful for nocturnal symptoms).
2. Glucocorticoids are the most effective treatment available for long term control.


Bottomline---

COPD: Anticholinergics are most effective. Home O2 therapy lowers mortality when sats <88%

Asthma: Steroids (inhaled/systemic depending on the severity)

beta2-adrenoceptor agonists (SABA) for both to dilate the airways.
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Old 04-24-2012
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thank you so much, NOVOBIOCIN... that information will really help
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