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Old 05-12-2012
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Kidney Hepato Renal Syndrome; no response to saline bolus

Hi friends can i have a question regarding hepatorenal syndrome . it says one of the diagnostic feature of HRS is no improvement of renal failure after 1.5 l of normal saline . can some one explain what is it about ?

Thanks
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Old 05-12-2012
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in contrast to pre-renal ARF, pt who develop HRS doesn't respond to fluid challenge, by the way the real cause of this synd is idiopathic, cuz the kidney is intact on biopsy and it's not from pre-renal origin.
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Quote:
Originally Posted by bisho View Post
in contrast to pre-renal ARF, pt who develop HRS doesn't respond to fluid challenge, by the way the real cause of this synd is idiopathic, cuz the kidney is intact on biopsy and it's not from pre-renal origin.
thank u..............
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Old 05-13-2012
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Quote:
Originally Posted by bisho View Post
in contrast to pre-renal ARF, pt who develop HRS doesn't respond to fluid challenge, by the way the real cause of this synd is idiopathic, cuz the kidney is intact on biopsy and it's not from pre-renal origin.
The best theory right now is that vasodilation of the splanchnic circulation steals volume and causes renal vasoconstriction - it's treated with vasoconstrictors like midodrine (weird, right?)
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Originally Posted by Mondoshawan View Post
The best theory right now is that vasodilation of the splanchnic circulation steals volume and causes renal vasoconstriction - it's treated with vasoconstrictors like midodrine (weird, right?)
ya even i thought so . I searched on web . It says that it causes splanchnic vasoconstriction
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