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Old 05-15-2012
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Kids DDx of short stature in child

the main DDx are:
GH def
Constitutional delay
Familial
Systemic condition
Hypothyroid
Psychosocial dwarfism

what are the Clue for each of them, and how we can differentia b/w Systemic condition and GH Def (cuz both will have CA>BA & abnormal Growth velocity)
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Old 05-15-2012
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GH deficiency might show stuff with decrease in other pituitary hormones too.
isolated GH deficiency is rare
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Old 05-15-2012
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Quote:
Originally Posted by bisho View Post
the main DDx are:
GH def
Constitutional delay
Familial
Systemic condition
Hypothyroid
Psychosocial dwarfism

what are the Clue for each of them, and how we can differentia b/w Systemic condition and GH Def (cuz both will have CA>BA & abnormal Growth velocity)

Hypothyroid: growth failure, mental retardation, TSH levels are high, umbilical hernia, sleeps a lot, etc.

Constitutional: I usually associate this with familial although its cause can also be idiopathic. So take a look at the parents or ask them about their pattern of growth. Most of the time they will have suffered from the same thing. Also, it has to be a uniform delay, growth, sexually, etc. More common in males.
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