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Old 05-29-2012
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Question diagnose this congenital anomaly !

A 22-year-old woman delivers a term infant. During her pregnancy, the mother had a documented viral infection. Both of the infantís pupils have the appearance shown in the figure when a light is shone into the eyes. Additional findings on physical exam include sensorineural deafness, splenomegaly, and microcephaly. Which of the following viruses is most likely responsible for the childís ocular disorder and the associated physical findings?
A. Cytomegalovirus
B. Epstein-Barr virus
C. Herpes simplex virus
D. Human immunodeficiency virus (HIV)
E. Rubella virus

diagnose this congenital anomaly !-jxf034f1.jpg
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Old 05-29-2012
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Quote:
Originally Posted by tyagee View Post
A 22-year-old woman delivers a term infant. During her pregnancy, the mother had a documented viral infection. Both of the infantís pupils have the appearance shown in the figure when a light is shone into the eyes. Additional findings on physical exam include sensorineural deafness, splenomegaly, and microcephaly. Which of the following viruses is most likely responsible for the childís ocular disorder and the associated physical findings?
A. Cytomegalovirus
B. Epstein-Barr virus
C. Herpes simplex virus
D. Human immunodeficiency virus (HIV)
E. Rubella virus
E.........
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Old 05-29-2012
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rubella??
congenital cataracts and deafness?
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E. Rubella virus
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Old 05-29-2012
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Image showing cataract nd question stem telling viral infection during pregnancy+congenital cataract+deafness+microcephaly+(heart defect esp. PDA i.e. not mentioned in d stem)>>>>Congenital rubella syndrome due to ~~E) Rubella infection.
All other options r not applicable except CMV infection resulting cytomegalic inclusion disease where all other characteristics described above are present excluding cataract which only found in CRS.
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Old 05-30-2012
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ans is A...CMV

here is the qbank expln


Quote:
Explanation
Option A (Cytomegalovirus) is correct. The appearance of the pupil indicates the presence of a cataract. Among the choices available, intrauterine CMV infection is the most likely cause of bilateral congenital cataracts.

Quote:
Option E (Rubella virus) is incorrect. Rubella virus classically causes bilateral congenital cataracts. In the United States, this intrauterine infection has become, thankfully, extraordinarily rare. Among the choices available, intrauterine CMV infection is the most likely cause of bilateral congenital cataracts.
this is what i call "anal".

learning point...both cmv and rubella can cause hearing loss and cataracts. and cmv is more common and rubella is less common.

comments?
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Originally Posted by tyagee View Post
ans is A...CMV

here is the qbank expln







this is what i call "anal".

learning point...both cmv and rubella can cause hearing loss and cataracts. and cmv is more common and rubella is less common.

comments?

this info is really new to me......thnx for sharing
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new concept but relevantly correct explanation. That was really a nice question to deal with. Thnx tyagee for posting that.
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