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Old 06-30-2012
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Question TOF tet spells and beta blockers

Hi friends , I have a question how does beta blocker help in treatment of TOF - Hypercyanotic spells ??

Thanks .
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Old 06-30-2012
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This is interesting. It may sound counterintuitive to me because we want to ⬆peripheral vascular resistance in TOF to ⬇right to left shunting ➡ ⬆pulmonary flow.

O well:


-UTD
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Old 07-01-2012
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These may be treated with beta-blockers such as propranolol, but acute episodes may require rapid intervention with morphine to reduce ventilatory drive and a vasopressor such as epinephrine, phenylephrine, or norepinephrine to increase blood pressure. Oxygen (100%) is effective in treating spells because it is a potent pulmonary vasodilator and systemic vasoconstrictor. This allows more blood flow to the lungs. There are also simple procedures such as squatting and the knee chest position which increases aortic wave reflection, increasing pressure on the left side of the heart, decreasing the right to left shunt thus decreasing the amount of deoxygenated blood entering the systemic circulation.
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Old 07-01-2012
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check this article with the link below. I hope it clarifies you better

http://www.educus.com/Journals/R18089616-0.html

[Propranolol: a new indication for an old drug in preventing postoperative junctional ectopic tachycardia after surgical repair of tetralogy of Fallot.]
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