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Old 06-28-2010
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Liver Diagnosis of Hemochromatosis

A Kaplan qbank question is saying that the best diagnostic test in a patient with hemochromatosis is testing for the C282Y mutation!
Do you agree with that, what about liver biopsy (which is mentioned in their notes)
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Old 06-28-2010
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I Think the first one for screening, the second one for diagnosis establishment
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Old 06-29-2010
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OK, this is what I found in "Master the Boards": best initial test is elevated serum iron and ferritin levels with a low TIBC, iron sat > 45%.
Most accurate test: liver biopsy. However, and MRI of the liver and the specific genetic test, the HFe gene (C282Y) mutation, in combination are sufficiently diagnostic to spare the patient a liver biopsy.
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Old 06-29-2010
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Question Is master the boards OK!

Thank you Dempsey, that makes sense.

But, are you reading Master the Boards Step 3 for the CK prep! Is it a good book of CK
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Old 06-29-2010
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Well I really like it because it's sometimes more straight forward than the Kaplan notes as far as "the best initial step" or "most accurate test". I feel that in the Kaplan notes they tell you all of the possible diagnostic tests, but sometimes they don't specify which one to answer in the question. I read somewhere that there is a Master the Boards for Step 2 CK in the works, but I don't know when it's going to be available. Hope it helps.
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Old 06-29-2010
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Link You can preorder it

Quote:
Originally Posted by dempsey View Post
I read somewhere that there is a Master the Boards for Step 2 CK in the works, but I don't know when it's going to be available. Hope it helps.
You can already preorder it from Amazon. It will be available on November 2nd, 2010.
Check it out here
Kaplan Medical USMLE Master the Boards Step 2 CK
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