compensation for chronic respiratory acidosis in COPD :-( - USMLE Forums
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Old 07-10-2012
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Lungs compensation for chronic respiratory acidosis in COPD :-(

COPD is chronic hypercapnic state. right. so kidneys will suck in bicarbonate as compensation.

now here are 2 excerpts from usmle world...which are both in context of COPD...which one is true ?

Quote:
(in chronic respiratory acidosis, HC03 - is expected to increase by 3.5 mEq/L for every 10 mmHg increase in pC02 ).
Quote:
The body compensates for chronic hypercapnia by increasing renal bicarbonate retention. Typically 0.1
mEq/L of bicarbonate is retained for every 1 mmHg increase in pC0 2.
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Old 07-10-2012
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Former is for Chronic Respi Acidosis, which is seen in COPD.

Latter is for Acute Respi Acidosis. Which is approximately 10 mEq/L / 10 mmHg. (Just multiplying by 10 to see how it works, but level is 0.1/1).

Awesome website for acid-base problems: http://www.manuelsweb.com/abg.htm
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Old 07-11-2012
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thank you so much. i gonna cram it.1/10 is pretty amazing hah

how you doing abg ?

those compensations are driving me crazy.

let me summarize here...

for chronic hyperCO2...3.5/10
for acute PaCO2 retention...1/10
for metabolic acidosis...the great winters formula
for metabolic alkalosis...?
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