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Old 07-21-2012
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Question when to expect atheroembolic renal failure?

when to expect atheroembolic renal failure?

some source mention 3-4 days
other mention 3-4 weeks

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Old 07-21-2012
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Can be both

With respect to the clinical presentation of AERD, renal failure was defined as acute if a sudden 50% reduction of GFR was evident within 1 week after the precipitating event; subacute if the same deterioration occurred in a stepwise fashion over 2 to 6 weeks; and chronic if the patient had a stable chronic renal impairment mimicking nephroangiosclerosis.
Atheroembolic renal disease develops when atheromatous aortic plaques rupture, releasing cholesterol crystals into the small renal arteries. Embolisation often affects other organs, such as the skin, gastrointestinal system, and brain. Although the disease can develop spontaneously, it usually develops after vascular surgery, catheterisation, or anticoagulation. The systemic nature of atheroembolism makes diagnosis difficult. The classic triad of a precipitating event, acute or subacute renal failure, and skin lesions, are strongly suggestive of the disorder. Eosinophilia further supports the diagnosis, usually confirmed by biopsy of an affected organ or by the fundoscopic finding of cholesterol crystals in the retinal circulation. Renal and patient prognosis are poor. Treatment is mostly preventive, based on avoidance of further precipitating factors, and symptomatic, aimed to the optimum treatment of hypertension and cardiac and renal failure. Statins, which stabilise atherosclerotic plaques, should be offered to all patients. Steroids might have a role in acute or subacute progressive forms with systemic inflammation.
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Cardiology-, Internal-Medicine-, Nephrology-

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