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  #1  
Old 08-11-2012
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Blood Blood Transfusion Reaction

TRANSFUSION REACTIONS !

Please diagnose each of the transfusion reactions

1. Mild febrile reaction with the first unit of blood. With the second unit there is shortness of breath and pulmonary infiltrates that resolve in 24 hours.

*** why patient was just febrile in 1st BT but not in 2nd BT !

2. Immediate anaphylaxis after a transfusion

3. Mild urticarial reaction after transfusion. No evidence of hemolysis.

4. A single-degree-centigrade elevation in temperature with no evidence of hemolysis

***

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Old 08-12-2012
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TRANSFUSION REACTIONS !

Please diagnose each of the transfusion reactions

Quote:
1. Mild febrile reaction with the first unit of blood. With the second unit there is shortness of breath and pulmonary infiltrates that resolve in 24 hours.
Mild febrile illnes with first unit of blood transfuion is most lkely Febrile non hemolytic transfusion reaction.

Shortness of breath after 2 nd transfusion is possibily due to TRALI( Transusion related acute lung injury)
Quote:
*** why patient was just febrile in 1st BT but not in 2nd BT !
? ?

Quote:
2. Immediate anaphylaxis after a transfusion
Blood transfusion to IgA def patients

Quote:
3. Mild urticarial reaction after transfusion. No evidence of hemolysis.

Allergic reaction IgE mediated to allergents in Blood

Quote:
4. A single-degree-centigrade elevation in temperature with no evidence of hemolysis
Febrile non hemolytic transfusion reactions.

***

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Febrile Transfuion Reaction,TRALI ,Anphylactic transfusion reations..

http://www.cdc.gov/bloodsafety/basics.html
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Old 08-12-2012
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I would add Acute Hemolytic Transfusion reaction: 1 hour after transfusion is started, is life threatning do to ABO mismatch: fever, chills, flank pain, hemoglobinuria, and a positive coombs test. Complications: DIC, acute renal failure, and shock.
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