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Old 09-26-2012
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Default Hyperviscosity

A 57 year old woman presents to the office with pain in her right flank. The pain occurs when she coughs and rolls over in her bed. She felt a pop when she coughed. Her past medical history is significant for vertebral compression fractures. The patient is found to have a profound high IgG level. The bone marrow biopsy show increased plasma level. There is no dyspnea ,visual disturbances or confusion

Which of the following is the explanation for the absence of signs of hyperviscosity ,such as dyspnea ,visual disturbances and confusion?

A. Hyperviscosity does not occur until late in the disease
B. Hyperviscosity does not occur until treatment begins
C. Hyperviscosity does not occur while renal function is intact
D. Hyperviscosity does not occur because of the size of the Immunoglobulins
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Old 09-26-2012
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D, eventho hyperviscocity can occur, IgG is 10 times smaller than IgM, so for hyperviscocity to occur the patient either has pretty bad luck or will die before it happens.
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Old 09-26-2012
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Quote:
Originally Posted by step_enhancer View Post
A 57 year old woman presents to the office with pain in her right flank. The pain occurs when she coughs and rolls over in her bed. She felt a pop when she coughed. Her past medical history is significant for vertebral compression fractures. The patient is found to have a profound high IgG level. The bone marrow biopsy show increased plasma level. There is no dyspnea ,visual disturbances or confusion

Which of the following is the explanation for the absence of signs of hyperviscosity ,such as dyspnea ,visual disturbances and confusion?

A. Hyperviscosity does not occur until late in the disease
B. Hyperviscosity does not occur until treatment begins
C. Hyperviscosity does not occur while renal function is intact
D. Hyperviscosity does not occur because of the size of the Immunoglobulins

D.) the difference of size between IgG and IgM
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Old 09-27-2012
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Originally Posted by XpaezX View Post
D, eventho hyperviscocity can occur, IgG is 10 times smaller than IgM, so for hyperviscocity to occur the patient either has pretty bad luck or will die before it happens.
Yes perfect ,right answer
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