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Old 11-08-2012
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Question prostate cancer with cord compression

friends,
patient has prostate cancer+ cord compression > steroids given > MRI done > what is next step in mx ?
  • Radiation
  • Flutamide
  • ketoconazole
or any thing else

i think RT but i dont know why...

thoughts?
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Old 11-08-2012
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Radiation to reduce the local tumor burden and hence the chance of compression.
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Old 11-08-2012
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Remove Prostrate then orchidectomy bilaterally followed by radiation therapy is the modality for metastatic prostrate carcinoma....
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Old 11-08-2012
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Quote:
Originally Posted by tyagee View Post
friends,
patient has prostate cancer+ cord compression > steroids given > MRI done > what is next step in mx ?
  • Radiation
  • Flutamide
  • ketoconazole
or any thing else

i think RT but i dont know why...

thoughts?
i think the next step in managment is Radation to decrease the tumour size..Other treatment modality has only a limited role...



Harrison...
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Old 11-08-2012
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Management of prostate cancer is very complicated but

Surgery to remove prostate is practically never done for Metastastic prostrate carcinoma

Quote:
Treatment by watchful waiting/active surveillance, HIFU, external beam radiation therapy, brachytherapy, cryosurgery, and surgery are, in general, offered to men whose cancer remains within the prostate. Hormonal therapy and chemotherapy are often reserved for disease that has spread beyond the prostate.


Prostate Cancer Treatment Protocols

Quote:
Selecting initial treatment requires assessing the risk of the disease spreading or progressing, which is based on evaluating life expectancy, comorbidities, biopsy grade (Gleason score), clinical stage, and prostate-specific antigen (PSA) levels of patients.
Quote:
Patients diagnosed with impending paralysis due to spinal cord compression or patients with pathologic fractures should be immediately immobilized until appropriate consultations are obtained.
Consultations

Consultation with a radiation oncologist should be obtained for palliative radiation therapy for bone metastases and for locally extensive tumors and on an emergent basis for spinal cord compression. Also consider consultations with a neurosurgeon for spinal cord compression, an orthopedic surgeon for pathologic fractures, and a medical oncologist for chemotherapy.
Radiation Treatment

Quote:
In patients with metastatic prostate cancer, radiation is also applied for palliative purposes. It is used in patients with hormone-refractory disease with painful bone metastases and in patients with impending spinal cord compression.
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Last edited by Novobiocin; 11-08-2012 at 06:08 PM.
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