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Old 11-21-2012
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Default Carcinoma associated with PCOS

A 45-year-old African-American woman who had been diagnosed with polycystic ovary syndrome (PCOS) in her early 20s presents to her gynecologist for her annual visit. One of her close friends has recently been diagnosed with ovarian cancer, so she is concerned about her own cancer risk. Menarche was at age 14, and she has yet to go through menopause. She has a healthy 19-year-old daughter. She has no family history of cancer. She does not smoke ordrink and exercises regularly. Aside from a diagnosis of PCOS, she is otherwise in good health. Given her health history, which of the following is true?

(A) She should have annual mammograms, although her risk of breast cancer is not changed relative to women without PCOS
(B) She should have annual mammograms because she has an increased risk of developing breast cancer relative to women without PCOS
(C) She should have annual Pap smears, although she has a decreased risk of developing cervical cancer relative to women without PCOS
(D) She should have annual Pap smears because she has an increased risk of developing cervical cancer relative to women without PCOS
(E) She should have annual Pap smears because she has an increased risk of developing ovarian cancer relative to women without PCOS
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Old 11-21-2012
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Quote:
Originally Posted by heartbeat View Post
A 45-year-old African-American woman who had been diagnosed with polycystic ovary syndrome (PCOS) in her early 20s presents to her gynecologist for her annual visit. One of her close friends has recently been diagnosed with ovarian cancer, so she is concerned about her own cancer risk. Menarche was at age 14, and she has yet to go through menopause. She has a healthy 19-year-old daughter. She has no family history of cancer. She does not smoke ordrink and exercises regularly. Aside from a diagnosis of PCOS, she is otherwise in good health. Given her health history, which of the following is true?

(A) She should have annual mammograms, although her risk of breast cancer is not changed relative to women without PCOS
(B) She should have annual mammograms because she has an increased risk of developing breast cancer relative to women without PCOS
(C) She should have annual Pap smears, although she has a decreased risk of developing cervical cancer relative to women without PCOS
(D) She should have annual Pap smears because she has an increased risk of developing cervical cancer relative to women without PCOS
(E) She should have annual Pap smears because she has an increased risk of developing ovarian cancer relative to women without PCOS
Option B. Unopposed Estrogen due to an-ovulation.
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it increases the risk of endometrial cancer.
so i would go with A
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(B) She should have annual mammograms because she has an increased risk of developing breast cancer relative to women without PCOS
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The correct answer is B. PCOS is associated with an increased risk of breast and endometrial cancer secondary to unopposed estrogen secretion
The new concept for me is that PCOS is not risk factor for Ovarian cancer

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Originally Posted by slamdunk View Post
it increases the risk of endometrial cancer.
so i would go with A(She should have annual mammograms, although her risk of breast cancer is not changed relative to women without PCOS)
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(B) She should have annual mammograms because she has an increased risk of developing breast cancer relative to women without PCOS
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Old 11-22-2012
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Quote:
Originally Posted by heartbeat View Post
The correct answer is B. PCOS is associated with an increased risk of breast and endometrial cancer secondary to unopposed estrogen secretion
The new concept for me is that PCOS is not risk factor for Ovarian cancer

Generally any condition which causes an-ovulation would be protective against the Ovarian Ca. E.g, OCPs, PCOS etc.
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