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Old 12-23-2012
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Stats Combining data from several studies

A cardiologist wishes to compare outcomes of medical management and cardiac catheterization for myocardial infarct presentation to the emergency department. She conducts a literature search and statistically combines the data from seven published studies. Which of the following is an advantage of this type of study?

(A) Ability to overcome poor study design in individual studies
(B) Less bias than other types of studies
(C) May allow detection of small differences between outcomes
(D) Pooled data already represent sufficiently similar populations and interventions
(E) Statistical analysis of pooled data is straightforward
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Old 12-23-2012
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B) Less bias than other types of studies ??
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i think its A. ability to overcome poor study designs in individual studies.
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(B) Less bias than other types of studies
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I think it is C.
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B...its meta analysis
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Correct Answer

The correct answer is C. The type of study described is known as a meta-analysis. Combining results from several studies enhances statistical precision and may allow a statistically significant result from the combined analysis that did not reach a significant level when each smaller study was analyzed alone.

Answer A is incorrect. Meta-analyses are limited by the quality of individual studies and do not resolve flaws in those studies, although the impact of any single flawed study may be lessened.

Answer B is incorrect. Performing a metaanalysis does not remove or decrease the bias inherent in each study, and may have a compounding effect of each study’s individual bias.
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