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Old 01-20-2013
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Lungs Cystic Fibrosis Complications?

A 5-month-old infant has failed to gain weight despite a good appetite. The child’s mother reports that the baby has up to eight bulky, foulsmelling, oily stools per day. A sweat chloride test reveals a chloride level of 78 mEq/L (normal: <60 mEq/L). Which of the following sequelae is most likely to occur as a result of this patient’s disease?
(A) Cirrhosis and subsequent hepatic failure
(B) Dehydration, electrolyte abnormalities, and acute hypotension
(C) Esophageal ulceration or strictures and upper gastrointestinal bleeding
(D) Purple lines on the gums, red-brown discoloration of the urine, and renal tubular acidosis
(E) Recurrent airway disease with eventual respiratory insufficiency associated with bronchiectasis
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Old 01-20-2013
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(E) Recurrent airway disease with eventual respiratory insufficiency associated with bronchiectasis
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Old 01-20-2013
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Confuse between (E) Recurrent airway disease with eventual respiratory insufficiency associated with bronchiectasis
(B) Dehydration, electrolyte abnormalities, and acute hypotension= this is most likely occurs with exercise in patient with cystic fibrosis
But i will go with ans--E
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Old 01-21-2013
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E - Bronchiectasis, complication of CF
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Old 01-21-2013
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This patient has cystic fibrosis (CF), which may be diagnosed in childhood with failure to thrive and failure to gain weight despite a good appetite. Children often have bulky, foul-smelling stools as a result of pancreatic insufficiency. CF disease in the lung accounts for most of the morbidity and mortality from this disease. Bacteria in the lungs of patients with CF, typically Pseudomonas or Burkholderia cepacia, infect the bronchial tree, provoking an intense inflammatory response. Infection stimulates mucus production,and damage to the wall of the airway with resultant bronchiectasis ensues.
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