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Old 03-17-2013
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Default Allergic interstitial nephritis???? Most accurate test

For allergic Interstitial nephritis the most accurate test is Hansel Test or Biopsy?
As in the videos Fisher says Biopsy is the most accurate test but in MTB-2 says Hansels test is most accurate?
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Old 03-17-2013
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Biopsy is the most accurate test but is not always needed or done. The Hansel test is sufficient to initiate management. The management opted here is to simply discontinue the offending drug causing the allergic interstitial nephritis.
An improvement in symptoms following discontinuation of drug is confirmatory of the diagnosis.
The Hansel test however is around 60% sensitive and 80% specific of the diagnosis. But this is sufficient and biopsy is not needed.
When is biopsy needed? Biopsy is the only way to actually make the diagnosis. An accurate diagnosis is needed when the patient is critical and management is crucial. The physician will not be able to wait and see if removing the drug will improve the symptoms.
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Old 03-19-2013
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But this is sufficient and biopsy is not needed.
When is biopsy needed? Biopsy is the only way to actually make the diagnosis. An accurate diagnosis is needed when the patient is critical and management is crucial. The physician will not be able to wait and see if removing the drug will improve the symptoms.
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