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Old 04-16-2013
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Poison Naloxone versus Naltrexone

Hi to all,

What are the basic differences for NALOXONE and NALTREXONE? Like indications, use, etc. It gets kinda confusing at times.
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Old 04-20-2013
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Quote:
Originally Posted by mcKoi View Post
Hi to all,

What are the basic differences for NALOXONE and NALTREXONE? Like indications, use, etc. It gets kinda confusing at times.
***
Here is what I know
Technically, both of them has the same uses and profile except for few things:
NALTREXONE has a longer duration of action. This would make it a better choice in treating a person overdosed on long acting opioid and to decrease craving. Its more hepatotoxic than NALOXONE.
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Old 04-21-2013
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The main difference between the 2 is the route of administration:

Naltrexone is administered orally while naloxone is given IV, and so it's given in emergency situations.
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Old 04-21-2013
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thanks Zamalek and Awwad
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