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Old 05-03-2013
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Pediatrics The most likely cause of Jaundice

Anewborn who has been exclusive breast fed now presents by her mother with the history of yellowish discoloration of the whole body. on examination there is tempr of 98 F. LIVER and Spleen not palpable. lab values shows increased indirect bilirubin. the most likely diagnosis is
a) breast feeding jaundice
b) criggler najjar syndrome 2
c) gilbert syndrome
d) dubin johnson syndrome
e) neonatal sepsis
f) viral hepatitis
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Old 05-03-2013
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thanks for the question @rupesh...

A) breast feeding jaundice
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Old 05-04-2013
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Given the current presentation in this case, I will state that is
A) Breast feeding jaundice in which the bilirubin can increased up to 20mg/dl. Normal levels would be 5-6mg/dl.
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Old 05-04-2013
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Correct Answer a

coz breast milk inhibits UDP glucuronyl transferase ,,,
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Old 05-04-2013
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Quote:
Originally Posted by rupesh View Post
coz breast milk inhibits UDP glucuronyl transferase ,,,
Don't confuse breast-milk jaundice with breast-feeding jaundice. Its a common mistake. This is breast-feed jaundice, it doesn't inhibit udp-glucouronosyl transferase. The baby is not being fed properly in this scenario. The question is poorly structured, with no time line or babys initial birth weight and current birth weight. Also, Im not sure if the mechanism for breast-milk jaundice involves UDP-glucotransferase inhibition. In UW, it says there's a protein in the breast milk which the baby can not tolerate in the case of breast-milk jaundice.
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Old 05-04-2013
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Quote:
Originally Posted by venky2600 View Post
thanks for the question @rupesh...

A) breast feeding jaundice
Am I missing something here? This can be both, Crigler Najar 2 & Breast Feeding jaundice, no?
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Quote:
Originally Posted by drsaid View Post
Am I missing something here? This can be both, Crigler Najar 2 & Breast Feeding jaundice, no?
hey, ya both can be....but crigler najjar type 2 is very rare than breast feeding jaundice.......so i thought it's the most appropriate to choose...
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Old 05-04-2013
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@dr said thanks for your feedback....option sud be breast milk jaundice in the neonate.....
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