The risk of Influenza in pregnant women - USMLE Forums
USMLE Forums Logo
USMLE Forums         Your Reliable USMLE Online Community     Members     Posts
USMLE Articles
Go Back   USMLE Forums > USMLE Step 2 CK Forum

USMLE Step 2 CK Forum USMLE Step 2 CK Discussion Forum: Let's talk about anything related to USMLE Step 2 CK exam

Thread Tools Search this Thread Display Modes
Old 11-09-2010
USMLE Forums Scout
Steps History: Step 1 Only
Posts: 22
Threads: 11
Thanked 13 Times in 4 Posts
Reputation: 23
ObGyn The risk of Influenza in pregnant women

Which of the following groups is least likely to have complicated Influenza infection?

A- Women in their first trimester of pregnancy
B- Women in their second trimester of pregnancy
C- Women in their third trimester of pregnancy
D- Women in the postpartum period
Reply With Quote Quick reply to this message

Old 11-09-2010
USDreamer's Avatar
USMLE Forums Scout
Steps History: Step 1 Only
Posts: 13
Threads: 5
Thanked 11 Times in 5 Posts
Reputation: 21

I think it's the postpartum period
Immunity is compromised throughout pregnancy so D is the right answer seems
Reply With Quote Quick reply to this message
Old 11-15-2010
USMLE Forums Guru
Steps History: Step 1 Only
Posts: 487
Threads: 95
Thanked 1,466 Times in 358 Posts
Reputation: 1476

OBJECTIVE: To determine whether maternal influenza virus infection in the second and third trimesters of pregnancy results in transplacental transmission of infection, maternal auto-antibody production or an increase in complications of pregnancy.

DESIGN: Case-control cohort study.

POPULATION: Study and control cohorts were derived from 3,975 women who were consecutively delivered at two Nottingham teaching hospitals between May 1993 and July 1994. A complete set of three sera was available for 1,659 women.

METHODS: Paired maternal ante- and postnatal sera were screened for a rise in anti-influenza virus antibody titre by single radial haemolysis and haemagglutination inhibition. Routine obstetric data collected during and after pregnancy were retrieved from the Nottingham obstetric database. Cord samples were tested for the presence of IgM anti-influenza antibodies, and postnatal infant sera were tested for the persistence of influenza-virus specific IgG. Paired antenatal and postnatal sera were tested against a standard range of auto-antigens by immunofluorescence.

MAIN OUTCOME MEASURES: Classification of women as having definite serological evidence of an influenza virus infection in pregnancy (cases) or as controls.

RESULTS: Intercurrent influenza virus infections were identified in 182/1,659 (11.0%) pregnancies. None of 138 cord sera from maternal influenza cases was positive for influenza A virus specific IgM. IgG anti-influenza antibodies did not persist in any of 12 infant sera taken at age 6-12 months. Six of 172 postnatal maternal sera from cases of influenza were positive for auto-antibodies. In all cases the corresponding antenatal serum was also positive for the same auto-antibody. There were no significant differences in pregnancy outcome measures between cases and controls. Overall, there were significantly more complications of pregnancy in the cases versus the controls, but no single type of complication achieved statistical significance.

CONCLUSIONS: Influenza infection in the second and third trimesters of pregnancy is a relatively common event. We found no evidence for transplacental transmission of influenza virus or auto-antibody production in pregnancies complicated by influenza infections. There was an increase in the complications of pregnancy in our influenza cohort.
Reply With Quote Quick reply to this message


ObGyn-, Step-2-Questions

Quick Reply

Register Now

In order to be able to post messages on the USMLE Forums forums, you must first register.
Please enter your desired user name, your email address and other required details in the form below.
User Name:
Please enter a password for your user account. Note that passwords are case-sensitive.
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:
Medical School
Choose "---" if you don't want to tell. AMG for US & Canadian medical schools. IMG for all other medical schools.
USMLE Steps History
What steps finished! Example: 1+CK+CS+3 = Passed Step 1, Step 2 CK, Step 2 CS, and Step 3.

Choose "---" if you don't want to tell.

Favorite USMLE Books
What USMLE books you really think are useful. Leave blank if you don't want to tell.
Where you live. Leave blank if you don't want to tell.


Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.

Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Similar Threads
Thread Thread Starter Forum Replies Last Post
Psychiatric disorder of postpartum women khushboo USMLE Step 1 Forum 11 02-05-2012 04:27 PM
Pregnant Mother Emancipation in USA? hunath USMLE Step 1 Forum 11 09-08-2011 01:00 PM
Reaction to Influenza Vaccine! dezirablize USMLE Step 2 CK Forum 3 10-14-2010 02:04 PM
Young Women with dull chest pain? Hohepa USMLE Step 2 CK Forum 5 04-10-2010 02:09 PM
Post Influenza Bacterial Pneumonia Estabrak USMLE Step 1 Forum 1 12-03-2009 03:12 PM

RSS Feed
Find Us on Facebook
vBulletin Security provided by vBSecurity v2.2.2 (Pro) - vBulletin Mods & Addons Copyright © 2017 DragonByte Technologies Ltd.

USMLE® & other trade marks belong to their respective owners, read full disclaimer
USMLE Forums created under Creative Commons 3.0 License. (2009-2014)