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Old 09-09-2013
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GIT Head Injury and Gastric Perforation; How?

Risk factor for gastric perforation :
- NSAID
- H pylori
- Burn
- Head injury
- Trauma
- Cancer

How?
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Old 09-09-2013
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Default n.vagus

I dont know about perforation, but head injury can cause cerebral edema, which increases intracranial pressure, what irritates the vagus. As you know, its responsible for gastric secretion of HCL. Extra secretion can irritate gastric mucosa and lead to ulcers.
Hope, I remember that right
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Old 09-10-2013
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The ulcer from the head injury causes the perforation. it is like saying NSAIDS cause perforation? how? no prostaglandins leads to no vasodilation of blood vessels leading to no mucosa health--> HCL damaging the mucosa-->Ulcer--> possible perforation.
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Old 09-11-2013
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They Stomach ulcers following a head injury are called Cushing ulcers, and although relatively uncommon Medical school professors seem to be very fond of them. you can find more about their pathophysiology if you follow this link

http://en.wikipedia.org/wiki/Cushing_ulcer
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Gastroenterology-, Internal-Medicine-, Neurology-

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