Post exposure prophylaxis for varicella - USMLE Forums
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  #1  
Old 09-19-2013
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Virus Post exposure prophylaxis for varicella

What's the post exposure prophylaxis norms for varicella in immunocompetent individuals? Is it vaccine plus immunoglobulin or only vaccine?
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  #2  
Old 09-19-2013
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Correct Answer

if exposure happened 3-5 days before and patient is immunocompeetnt. then only vaccine.....ideally within 3 days ..
if immunocompromised= only VZIG withing 4 days.....else observation only,
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Old 09-19-2013
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they update this in uw it is now for immunocompromised(with no history of prior infection or vaccine) VZIG within 10 days of exposure + follow up.
for immunocompetent(age 1yr or more) should receive vaccine even if they present after 5 days of exposure, it is ineffective in preventing infection after 5days but if transmission does not occur it can produce immunity for future exposure.
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Old 09-19-2013
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Quote:
Originally Posted by sonami View Post
they update this in uw it is now for immunocompromised(with no history of prior infection or vaccine) VZIG within 10 days of exposure + follow up.
for immunocompetent(age 1yr or more) should receive vaccine even if they present after 5 days of exposure, it is ineffective in preventing infection after 5days but if transmission does not occur it can produce immunity for future exposure.
i dnt know about updated uw but what cdc says is here....http://wwwnc.cdc.gov/travel/yellowbo...lla-chickenpox

i think we should consider cdc guideline not uw....
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  #5  
Old 09-20-2013
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logically the sooner the better but the thing is what to do if the pt present after the first 3-5 days of exposure.
the CDC mentioned the same thing regarding IVIG can be given as late as 10 days.
and regarding the vaccine they mentioned it's effective within the first 3- 5 days also the same thing and they did not mention after this 5 days you just observe.

recheck your link.
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