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Old 11-08-2013
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Eye Proliferative Retinopathy and Wet Macular Degeneration

Hi guys i stuck on ophthalmology...
Please help me to differentiate bw Proliferative diabetic retinopathy and Wet macular degeneration..
Also who can help with all possible fundoscopic finding-- will appreciate
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Old 11-09-2013
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both essentially look the same on a fundoscopic exam
Hx of diabetes VS age is the clue + macular degeneration wet type has more rapid deterioration of central vision


Important fundoscopic findings for your exam
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Old 11-09-2013
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Hi Draga.
For proliferative rethinopathy- neovascularisation(which will cover optic disc, normal optic disc should be free of vessels) + vitreous hemorrhage(new vessels will leak causing VITREOUS hemorrhage, patient will see floaters, fundoscopic exam can be difficult due to blood in vitreous humor obscuring retina visualization.) Note that in nonproliferative(background) retinopathy hemorrhages will be retinal, which will not worsen vision.

Wet ARMD - abnormal growth of choroidal vessels in subretinal space(they can leak -> SUBRETINAL hemorrhage - > exudative retinal deattachment->which will lead to rapid vision loss) + druzen formation(it is extracellular collection of deposits in subretinal space). This will lead to bilateral CENTRAL vision loss. Also you can treat wet ARMD - VEGF inhibitors, laser photo, photodinamic therapy with verteoporfin, whereas dry ARMD hasn't proven therapy.

And by the way - hajohutun kez ko parapelu mej!
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Old 11-09-2013
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Quote:
Originally Posted by Gikson View Post
Hi Draga.
For proliferative rethinopathy- neovascularisation(which will cover optic disc, normal optic disc should be free of vessels) + vitreous hemorrhage(new vessels will leak causing VITREOUS hemorrhage, patient will see floaters, fundoscopic exam can be difficult due to blood in vitreous humor obscuring retina visualization.) Note that in nonproliferative(background) retinopathy hemorrhages will be retinal, which will not worsen vision.

Wet ARMD - abnormal growth of choroidal vessels in subretinal space(they can leak -> SUBRETINAL hemorrhage - > exudative retinal deattachment->which will lead to rapid vision loss) + druzen formation(it is extracellular collection of deposits in subretinal space). This will lead to bilateral CENTRAL vision loss. Also you can treat wet ARMD - VEGF inhibitors, laser photo, photodinamic therapy with verteoporfin, whereas dry ARMD hasn't proven therapy.

And by the way - hajohutun kez ko parapelu mej!
ohh.. so i am not only armenian here
shnorhakalutyun qez nuynpes..
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Old 11-09-2013
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only difference that i knew -wet MD has central vision loss,,proliferative retinopathy has spot on vision-floaters...
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