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Old 02-09-2014
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ObGyn Anovulation

One concept is secondary amenorrhea can occur due to anovulation which we check with the help of progestrone challenge test which leads to withdrawl bleeding if adequate estrogen is present.
In other concept anovulation can lead to intermenstrual bleeding due to unopposed action of estrogen on the endometrium which leads to its proliferation and makes the endometrium unstable which can lead to irregular bleeding.

just confused here. Can any one plz clarify the things.

In first concept it leads to amenorrhea and in other it leads to irregular bleeding.
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Old 02-09-2014
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Both are true.

Estrogen cause proliferation while progesteron stabilize it and withdrawal of P will cause shedding. In case of unoppose E, the endometrial lining will grow, grow, grow (hence amenorrhea) until the arterioles can't support it any longer then it will shed as irregular bleeding w/o spasm/dysmenorrhea.
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Old 02-09-2014
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Quote:
Originally Posted by IMlover View Post
Both are true.

Estrogen cause proliferation while progesteron stabilize it and withdrawal of P will cause shedding. In case of unoppose E, the endometrial lining will grow, grow, grow (hence amenorrhea) until the arterioles can't support it any longer then it will shed as irregular bleeding w/o spasm/dysmenorrhea.
thanks for your effort to explain the things!!!
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