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Old 01-26-2011
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Drug Intraluminal Treatment of Amebic Abscess!

In the treatment of amebic abscess they mention some "intraluminal" and "tissue" agents. Does anyone have an idea what are these and what's the difference????

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Old 01-26-2011
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Tissue agent: metronidazole
Kills the amebic invaders throughout tissue

Luminal agent: iodoquinol or paromomycin
Kills the cysts and free-roaming trophozites in the lumen of the GI tract


So, in invasive amebiasis, you'd treat with metro, followed by a luminal agent (to get rid of colonization and prevent re-infection). For asymptomatic amebiasis, you should certainly give a luminal agent, but the tissue agent is optional.
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Old 01-26-2011
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Kaplan recommends diloxanide for intraluminal ameba.
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Quote:
Originally Posted by usluipek View Post
Kaplan recommends diloxanide for intraluminal ameba.
Diloxanide furoate is not currently approved for use in the United States - would they still ask it on CK? It's good to know, anyway.
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Old 01-26-2011
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Quote:
Originally Posted by Mondoshawan View Post
Diloxanide furoate is not currently approved for use in the United States - would they still ask it on CK? It's good to know, anyway.

Diloxanide is approved by FDA !http://www.fda.gov/AboutFDA/CentersO.../ucm092199.htm
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