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Old 03-26-2014
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Help OB/Gyn treatment of endometrial carcinoma

Hi everyone,

When patients being diagnosed with endometrial carcinoma, surgery should be carried out. And through the pathological analysis of the sample, if it turns out to be metastatic one, chemotherapy will be put on stage. But anyone knows why progestins should also be given together with chemo drugs even without the presence of uterus?
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Old 03-26-2014
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i know that chemo with progestin used for tratment of young pt who want to have baby in future...this i found on internet..

<In place of surgery to remove the uterus, progestin therapy is sometimes used to treat stage IA, grade 1 endometrial cancer in young women who still want to have children. Progestin treatment can cause the cancer to shrink or even go away for some time, giving the woman a chance to get pregnant. It can be given as a pill, injection, or as a progestin containing intrauterine device. This approach is experimental and can be risky if the patient isn't watched closely. In many cases, it does not work. Sometimes the cancer keeps growing. Sometimes the tumor gets smaller or goes away for a while, but then comes back again. Not having surgery right away may give the cancer time to spread outside the uterus. A second opinion from a gynecologic oncologist and pathologist (to confirm the grade of the cancer) before starting progestin therapy is important. Patients need to understand that this is not a standard treatment and may increase risk.>
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Old 03-26-2014
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http://www.cancer.org/cancer/endomet...ating-by-stage
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