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Old 04-26-2011
lookingup's Avatar
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Listening diagnosis of cushing synd

just a revision...

first --comes 1mg overnight dexa
2nd 24 hr urinary cortisol.....
acth level...
high....(look up high in the body)...pitiutary or ectopic..
low....(look lower down at the body)..adrenal
high dose dexa test....
suppress acth...(high dose dexa able to knock out the peanut pituitary)
pituitary cause(since the peanut was defective n weak..so defeated
n found out!!!)
no suppress acth...(high dose dexa unable to knock the peanut pituitary
coz the peanut is not defective.so strong..look elsewhere)
ectopic...like carcinoid orthe lungs!!!
look up in life...always:)
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Old 04-26-2011
Seetal's Avatar
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Default here's another

overnight dexa test --> either normal or abnormal.

for abnormal test, proceed with 24hr urine free cortisol --> normal (no cushing) or abnormal (cushing syndrome)

then high dose dexa suppression test--> if suppressed, then its pituitary (cushing DISEASE), if not, then its either ectopic ACTH or adrenal cause.

NOW u do an ACTH level measurement test!

if its low --> adrenal neoplasia (cancer or adenoma)
if its high --> adrenal hyperplasia due to ectopic ACTH-producing tumor (think small cell ca of the lungs)--> proceed with a lung CT scan pronto!
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