Migraine (Abortive) therapy in a pregnant in the last trimester - USMLE Forums
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Old 06-01-2011
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Drug Migraine (Abortive) therapy in a pregnant in the last trimester

what do we give?

we cant give ergotamine/triptanes

and certaily not nsaids (closure of PDA)

what can we do?
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Old 06-01-2011
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Quote:
Originally Posted by docoftheworld View Post
what do we give?

we cant give ergotamine/triptanes

and certaily not nsaids (closure of PDA)

what can we do?
We can use acetaminophen. It is a pregnancy category B drug and safe to use in all stages
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Old 06-01-2011
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alright, though it closes PDA, thanks
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Old 06-01-2011
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NSAIDS close PDA. Acetaminophen is not an NSAID
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oooops u said aceta not indometha sorrrrry
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Old 06-01-2011
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Yeah pharma sometimes gets me as well
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thanks again for replying
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Ergots

Ergotamine should not be used during pregnancy as it can increase the risk of miscarriage and perinatal death.

Paracetamol/acetaminophen is safe throughout pregnancy and lactation. Aspirin is also safe, but may cause bleeding problems if taken near term.

Prochlorperazine has been used for pregnancy-related nausea for many years.

Metoclopramide and domperidone are safe, but are probably best avoided during the first trimester

or continuing frequent attacks, which warrant daily preventative treatment, propranolol has best evidence of safety during pregnancy and lactation.

If you have taken triptans and then find you are pregnant, do not worry. However, continued use during pregnancy is not recommended.


http://www.migrainesurvival.com/fram...=38&cate_id=11
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