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Old 06-01-2011
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Neuro pseudotumor cerebri (idiopathic intracranail hypertension)

is the cause OVERproduction of CSF by the choroid plexus, OR Decreased absorption of CSF by arachnoid villi (the same as in Normopressure Hydrocephalus)?

hold your horses, i know acetazolamide treats PTC, but that doesnt mean the mechanism of it is increased production of CSF in all cases (vitamin A does increase CSF as far as know) ... what is your opinion?

Also, is there any relation beteen NPH and Hydroceph ex vacuo?
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Originally Posted by docoftheworld View Post
is the cause OVERproduction of CSF by the choroid plexus, OR Decreased absorption of CSF by arachnoid villi (the same as in Normopressure Hydrocephalus)?

hold your horses, i know acetazolamide treats PTC, but that doesnt mean the mechanism of it is increased production of CSF in all cases (vitamin A does increase CSF as far as know) ... what is your opinion?

Also, is there any relation beteen NPH and Hydroceph ex vacuo?
pseudotumor cerebri is possibly idiopathic, but if you ask me it happens a lot in those who are systemically hypertensive , and also might have some hormonal influences , given the fact that it happens so much in women of a particular age.

also, regarding your question about NPH and hydroceph ex vacuo , the pathophysiology is different , NPH presents differntly and its actually DUE to the CSF that there is neurological sign/symptom ( gait ataxia , dementia , incontinence).

In hydrocephalus ex vacuo - there is PRIMARY loss of cerebral tissue and this causes the dilatation of the cerebral ventricles.

Dont know how much i was able to explain, but hope it helps somewhat.
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its very much helpful, just one last question:

whats the main mechanism of Pseudotum cerebri
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its very much helpful, just one last question:

whats the main mechanism of Pseudotum cerebri
i was just reading , it might have to do with increased CSF production and/or obstruction of venous outflow from brain [ref wikipedia].
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so not impaired resorption by arachnoid villi
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Old 06-03-2011
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so not impaired resorption by arachnoid villi
I think it could be either..
Acetazolamide only helps because it decreases production of CSF not necessarily affecting the original pathology of the excess CSF
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got it thanks
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