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Old 06-13-2015
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Default Hematology case study question

Whats do you guys think for this case study??

A 43 year old South Vietnamese male presented with increasing fatigue. He had no previous complaints of ill-health.
The laboratory results were:
Hemoglobin: 50g/L
Hct: 0.18
MCV: 81 fl
MCH: 22.1 pg
Platelet count:200 x 109/L
White cell count: 4.0 x109/L
Normal differential
The blood film showed markedly increased numbers of microcytes, hypochromic and polychromatic cells, increased numbers of oval cells, tear drop cells, cell fragments, target cells and an occasional nucleated red cell was noted.

Hemoglobin electrophoresis on cellulose acetate at pH 8.6 revealed a band in the A2 region. This band accounted for 20% of the total hemoglobin.
HbF was raised at 5%.

Outline further investigations which should be performed explaining your reasoning.

Last edited by yepp87; 06-13-2015 at 02:36 AM. Reason: typo correction
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Old 06-14-2015
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Confirmatory study - genetic testing
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