A 1-year-old boy is brought to the physician by his parents due to repeated upper respiratory tract infections and oral fungal infections. Physical examination reveals low set ears and fish-like mouth. Laboratory tests reveal hypocalcemia and chest x-ray shows no thymus shadow.
What is the most likely cause of hypocalcemia in this case?
A-Decreased secretion of parathyroid hormone
B-End-organ hyposensitivity to parathyroid hormone
C-End-organ hyposensitivity to calcitonin
D-Increased secretion of calcitonin
E-Increased secretion of parathyroid hormone