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Old 09-13-2010
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heights heights is offline
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Although you may need the biopsy for a definite diagnosis, I think you should still know a bit about their presentations. Goodpasture's present with hematuria and hemoptosis ( because the antibodies that attack the glomerular basement membrane in the kidney's also attck basement membranes in the lung). The Pauci-immune RPGN's are mostly necrotizing vasculitis such as Wegener's, Churg- Strauss and microscopic polyangiitis, and they also have hematuria and hemoptosis, but they also have pupura and ANCA. Also, it seems that the pauci- immune diseases have more widespread systemic involvement than Goodpasture's. Hope that helps!
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