USMLE Forums - View Single Post - Causes of Rapidly Progressive Glomerulonephritis
View Single Post
  #3  
Old 09-13-2010
heights's Avatar
heights heights is offline
USMLE Forums Master
 
Steps History: Not yet
Posts: 557
Threads: 69
Thanked 1,086 Times in 358 Posts
Reputation: 1106
Default

Although you may need the biopsy for a definite diagnosis, I think you should still know a bit about their presentations. Goodpasture's present with hematuria and hemoptosis ( because the antibodies that attack the glomerular basement membrane in the kidney's also attck basement membranes in the lung). The Pauci-immune RPGN's are mostly necrotizing vasculitis such as Wegener's, Churg- Strauss and microscopic polyangiitis, and they also have hematuria and hemoptosis, but they also have pupura and ANCA. Also, it seems that the pauci- immune diseases have more widespread systemic involvement than Goodpasture's. Hope that helps!
Reply With Quote
The above post was thanked by:
rasheed (09-13-2010), rigbbm (04-23-2020)