USMLE Forums - View Single Post - Urea vs. Uric acid
View Single Post
Old 10-03-2010
ashishkabir's Avatar
ashishkabir ashishkabir is offline
USMLE Forums Master
Steps History: 1+CK+CS+3
Posts: 625
Threads: 19
Thanked 404 Times in 240 Posts
Reputation: 424

So uric acid goes into the brain and causes self mutilation, MR and choreoathetosis and
ammonia goes in to the brain and causes flapping tremor.

Urea then, is a good thing because if you can't make it then you've got a problem with the urea cycle and ammonia will accumulate.

However if Urea is increased, then depending on whether it's >15X the creatinine clearance in urine there's a kidney problem.

I get a little confused on this part too -

If BUN in urine is >15X creatinine in urine then the problem is with the kidney a nephrotic or nephritic syndrome or ATN or ARF or CRF etc...

If BUN is high but Bun / Creatinine is <15 then the problem is volume to the kidney is low for some reason - such as renal artery stenosis or CHF or something else

Is that right?
Reply With Quote