USMLE Forums - View Single Post - Basic Science - Adhesion Mechanisms
View Single Post
  #1  
Old 11-28-2010
schiwei's Avatar
schiwei schiwei is offline
USMLE Forums Scout
 
Steps History: Not yet
Posts: 81
Threads: 51
Thanked 48 Times in 19 Posts
Reputation: 47
Question Basic Science - Adhesion Mechanisms

What is the mechanism underlying chemoattraction and adhesion?
Do ICAM and VCAM on the surfaces of endothelial cells attach to integrins on leukocytes (e.g. LFA-1 and Mac-1). What roles do IL1, TNF, LTB4 and C5a
play in activating leukocyte adhesion molecules? That is do the latter two activate other adhesion molecules as well, while attaching themselves unto bacterial antigens?

Thanks so much in advance!
Reply With Quote