C) ↓ gh
Very nice, all of you are answered correct
Correct ans is C) ↓ GH
Octreotide is a somatostatin analogue. Accordingly, it will have a similar effect on the GH axis as somatostatin. GH will decrease in response to octreotide. Consequently, IGF-1 will also decrease since its secretion is downstream of GH stimulation at the liver (apx8 mentioned above). VIP will decrease since it too is inhibited by somatostatin (the reason for giving octreotide as a treatment for VIPoma). And finally, somatostatin will decrease because ↓ GH.
@apx85 - Somatostatin has no effect on K+, its just there as a choice to confuse students.