USMLE Forums - View Single Post - 1st step in pathogenesis of atherosclerosis caused by hyperlipidemia
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Old 01-01-2010
fauzan fauzan is offline
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according to robbins....

chronic endothelial injury is the first step followed by
accumulation of lipoprotein mainly LDL in the vessel wall, followed by
oxidation of lipoprotein,
adhesion of monocytes,
adhesion of macrophages,
trasformation into foam cells,
adhesion of platelets, and release of factors from platelets, maccrophages and vascular wall, leading to
SMC proliferation.....
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