The SPs are humans. In Huston and Chicago the faced many IMGs and they compare them to other IMGs. They adapt the accents and behaviors. But in Philly with no many IMGs they do not have experience with many accents and you would be compared with AMGs.
Many Japanese friends prefer to take the exam in LA because of this reason
( SPs are familiar with their accents because of high percentage of Japanese examinees).
Despite that I know many IMGs who passed in Philly and Many who failed in Chicago.
I know a friend, who doesn't have an accent even though she's not a US national and has a 109 on TOEFL but failed the exam in the CIS portion at Philladelphia despite passing the mock exam with flying colours. She was shocked since she felt she was just initially nervous and messed up with the first 2 patients. But she does remember that there were only 2 other IMGs at her centre. 3 out of 24 IMGs is definitely a poor ratio and so. . .I'm taking the exam in Chicago.
I have a friend who stuggles with grammar and gave his exam in Houston. Passed in first attempt.
I am an IMG from India but I lived in USA before for 5 years. I took the exam in Philadelphia. The exam center, the SPs and the staff were very nice and I thought the exam was easy. I got high performance in all three categories.
I do not think that exam center really matters for CS. Maybe for those with difficult accents, Houston maybe better because those SPs are used to hearing people with different accents. But otherwise, it doesn't matter.
I trust the USMLE as a standardized exam and you should take the exam where it is convenient for you.
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